ZFIN ID: ZDB-GENE-061013-428
Gene Name: actin filament associated protein 1-like 1b
Gene Symbol: afap1l1b    Nomenclature History

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Previous Names: sb:cb932, zgc:153096

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have SH3 domain binding activity. Predicted to localize to the cytosol. Is expressed in cardiovascular system; neural crest; and ventral mesoderm. Orthologous to human AFAP1L1 (actin filament associated protein 1 like 1).
Genome Resources: Alliance (1),  Gene:768144 (1),  Ensembl(GRCz11):ENSDARG00000056453 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44971 Point Mutation Unknown Unknown ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH afap1l1b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH afap1l1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component cytosol (more)
Molecular Function SH3 domain binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Family IPR030112 Actin filament-associated protein 1-like 1
Family IPR030113 Actin-filament associated protein
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA afap1l1b-201 (1)    Ensembl 2733
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM afap1l1b No data available
MARKER RELATIONSHIPS
afap1l1b Contained in: [BAC] DKEY-25L11 (1) (order this)
afap1l1b Encodes: [EST] cb932 (1) (order this)
[cDNA] MGC:153096 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001077287 (1)
Genomic GenBank:CR749164 (1) 211000 bp Blast at MegaBLAST
Polypeptide UniProtKB:E9QFQ2 (1) 754 aa
Sequence Information (all 16)
ORTHOLOGY for afap1l1b ( Chr: 21 )
CITATIONS (19)