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Gene

aplp2

ID
ZDB-GENE-061009-28
Name
amyloid beta (A4) precursor-like protein 2
Symbol
aplp2 Nomenclature History
Previous Names
  • fk52a05
  • si:dkey-11k4.3
  • wu:fk52a05
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable heparin binding activity; serine-type endopeptidase inhibitor activity; and transition metal ion binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in gill; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human APLP2 (amyloid beta precursor like protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aplp2 Human Ortholog
No data available
Associated With aplp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019744 Amyloidogenic glycoprotein, copper-binding domain conserved site
Conserved_site IPR019745 Amyloidogenic glycoprotein, intracellular domain, conserved site
Conserved_site IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
Domain IPR002223 Pancreatic trypsin inhibitor Kunitz domain
Domain IPR008154 Amyloidogenic glycoprotein, extracellular
Domain IPR011178 Amyloidogenic glycoprotein, copper-binding
Domain IPR015849 Amyloidogenic glycoprotein, heparin-binding
Domain IPR019543 Beta-amyloid precursor protein C-terminal
Domain IPR024329 Amyloidogenic glycoprotein, E2 domain
Family IPR008155 Amyloidogenic glycoprotein
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036176 E2 domain superfamily
Homologous_superfamily IPR036454 Amyloidogenic glycoprotein, heparin-binding domain superfamily
Homologous_superfamily IPR036669 Amyloidogenic glycoprotein, copper-binding domain superfamily
Homologous_superfamily IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
Domain Details Per Protein
Protein Length Amyloidogenic glycoprotein Amyloidogenic glycoprotein, copper-binding Amyloidogenic glycoprotein, copper-binding domain conserved site Amyloidogenic glycoprotein, copper-binding domain superfamily Amyloidogenic glycoprotein, E2 domain Amyloidogenic glycoprotein, extracellular Amyloidogenic glycoprotein, heparin-binding Amyloidogenic glycoprotein, heparin-binding domain superfamily Amyloidogenic glycoprotein, intracellular domain, conserved site Beta-amyloid precursor protein C-terminal E2 domain superfamily Pancreatic trypsin inhibitor Kunitz domain Pancreatic trypsin inhibitor Kunitz domain superfamily PH-like domain superfamily Proteinase inhibitor I2, Kunitz, conserved site
UniProtKB:A2BID8 764
UniProtKB:A0A2R8Q4V0 776
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations