ZFIN ID: ZDB-GENE-061009-28
Gene Name: amyloid beta (A4) precursor-like protein 2
Gene Symbol: aplp2    Nomenclature History

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Previous Names: fk52a05, si:dkey-11k4.3, wu:fk52a05

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have heparin binding activity; serine-type endopeptidase inhibitor activity; and transition metal ion binding activity. Predicted to localize to integral component of membrane. Is expressed in gill; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human APLP2 (amyloid beta precursor like protein 2).
Genome Resources: Alliance (1),  Gene:796801 (1),  Ensembl(GRCz11):ENSDARG00000054864 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
is23Gt Transgenic Insertion Intron 12 Unknown DNA
sa29086 Point Mutation Unknown Premature Stop ENU
sa29087 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH aplp2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH aplp2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component integral component of membrane (more)
Molecular Function heparin binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA aplp2-201 (1)    Ensembl 5379
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM aplp2 No data available
MARKER RELATIONSHIPS
aplp2 Contained in: [BAC] CH73-115E6 (1), DKEY-11K4 (1) (order this)
aplp2 Encodes: [EST] fk52a05
[cDNA] MGC:158408 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001123012 (1) 5427 nt
Genomic GenBank:BX908399 (1) 106712 nt
Select Tool
Polypeptide UniProtKB:A0A2R8Q4V0 (1) 776 aa
Sequence Information (all 22)
ORTHOLOGY for aplp2 ( Chr: 18 )
CITATIONS (25)