ZFIN ID: ZDB-GENE-061005-1
Gene Name: cyclic nucleotide gated channel subunit alpha 2a
Gene Symbol: cnga2a    Nomenclature History

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Previous Name: cnga5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Exhibits ion channel activity. Involved in cilium assembly and ion transport. Localizes to the integral component of membrane. Is expressed in brain; olfactory epithelium; spinal cord; and testis. Orthologous to human CNGA2 (cyclic nucleotide gated channel subunit alpha 2).
Genome Resources: Alliance (1),  Gene:751786 (1),  Ensembl(GRCz11):ENSDARG00000102968 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018821Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22446 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22447 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35663 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wz09 Indel Unknown Unknown CRISPR
    wz10 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cnga2a 2
    CRISPR2-cnga2a 2
    MO1-cnga2a N/A 1
    MO2-cnga2a N/A 1
    MO3-cnga2a N/A 1
    DISEASE ASSOCIATED WITH cnga2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cnga2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ion channel activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000595 Cyclic nucleotide-binding domain
    Domain IPR005821 Ion transport domain
    Homologous_superfamily IPR014710 RmlC-like jelly roll fold
    Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
    Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
    Domain IPR032406 Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cnga2a-201 (1)    Ensembl 2105
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cnga2a monoclonal Mouse IHC 3
    Ab2-cnga5 monoclonal Mouse IHC 1
    CONSTRUCTS WITH SEQUENCES FROM cnga2a No data available
    MARKER RELATIONSHIPS
    cnga2a Contained in: [BAC] DKEY-86A12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044746 (1) 2105 bp
    Genomic GenBank:CR376767 (1) 167993 bp
    Select Tool
    Polypeptide UniProtKB:Q0GFG2 (1) 673 aa
    Sequence Information (all 6)
    ORTHOLOGY for cnga2a ( Chr: 14 )
    CITATIONS (21)