Gene

tsen2

ID
ZDB-GENE-060929-918
Name
TSEN2 tRNA splicing endonuclease subunit
Symbol
tsen2 Nomenclature History
Previous Names
  • zgc:154067
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have tRNA-intron endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to localize to tRNA-intron endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2B. Orthologous to human TSEN2 (tRNA splicing endonuclease subunit 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tsen2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pontocerebellar hypoplasia type 2B Alliance Pontocerebellar hypoplasia type 2B 612389
Associated With tsen2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006677 tRNA intron endonuclease, catalytic domain-like
Domain IPR006678 tRNA intron endonuclease, N-terminal
Family IPR006676 tRNA-splicing endonuclease
Family IPR016589 tRNA-splicing endonuclease, SEN2 subunit
Homologous_superfamily IPR011856 tRNA endonuclease-like domain superfamily
Homologous_superfamily IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily
Domain Details Per Protein
Protein Length tRNA endonuclease-like domain superfamily tRNA intron endonuclease, catalytic domain-like tRNA intron endonuclease, catalytic domain-like superfamily tRNA intron endonuclease, N-terminal tRNA-splicing endonuclease tRNA-splicing endonuclease, SEN2 subunit
UniProtKB:A8E5A8 438
UniProtKB:F1QLQ4 187
UniProtKB:Q08BW3 438
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations