Gene

prkar1b

ID

ZDB-GENE-060929-580

Name

protein kinase, cAMP-dependent, regulatory, type I, beta

Symbol

prkar1b Nomenclature History

Previous Names

zgc:153624

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cGMP-mediated signaling. Predicted to localize to cytosol. Orthologous to human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prkar1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Marbach-Schaaf neurodevelopmental syndrome	619680

Associated With prkar1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018488	Cyclic nucleotide-binding, conserved site
Domain	IPR000595	Cyclic nucleotide-binding domain
Domain	IPR003117	cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
Domain	IPR042818	RIbeta, dimerization/docking domain
Family	IPR012198	cAMP-dependent protein kinase regulatory subunit
Homologous_superfamily	IPR014710	RmlC-like jelly roll fold
Homologous_superfamily	IPR018490	Cyclic nucleotide-binding-like