Gene

llgl1

ID
ZDB-GENE-060825-69
Name
LLGL scribble cell polarity complex component 1
Symbol
llgl1 Nomenclature History
Previous Names
  • zgc:153337
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity; Rab GTPase binding activity; and myosin II binding activity. Involved in cell projection assembly; regulation of Notch signaling pathway; and sensory system development. Localizes to basolateral plasma membrane. Is expressed in central nervous system; eye; head; and retina. Orthologous to human LLGL1 (LLGL scribble cell polarity complex component 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Clark et al., 2012
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With llgl1 Human Ortholog
No data available
Associated With llgl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR013577 Lethal giant larvae homologue 2
Domain IPR013905 Lethal giant larvae (Lgl)-like, C-terminal domain
Family IPR000664 Lethal(2) giant larvae protein
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Lethal(2) giant larvae protein Lethal giant larvae homologue 2 Lethal giant larvae (Lgl)-like, C-terminal domain WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E7FD67 1040
UniProtKB:E9QDL6 305
UniProtKB:I0BWE2 1040
UniProtKB:Q0P470 304
UniProtKB:F1QPI4 1014
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-llgl1 polyclonal Rabbit
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations