ZFIN ID: ZDB-GENE-060824-4
Gene Name: phosphodiesterase 5A, cGMP-specific, b
Gene Symbol: pde5ab    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: pde5a

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human PDE5A (phosphodiesterase 5A).
Genome Resources: Alliance (1),  Gene:553270 (1),  Ensembl(GRCz11):ENSDARG00000051915 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016182Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7093 Point Mutation Unknown Splice Site ENU
    sa21102 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34205 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pde5ab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pde5ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Molecular Function 3',5'-cyclic-nucleotide phosphodiesterase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pde5ab-203 (1)    Ensembl 2742
    ncRNA pde5ab-003 (1)    Ensembl 1665
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pde5ab No data available
    MARKER RELATIONSHIPS
    pde5ab Contained in: [BAC] CH211-127L8 (1), CH211-222K9 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001123260 (1) 2604 nt
    Genomic GenBank:BX664603 (1) 190963 nt
    Select Tool
    Polypeptide UniProtKB:F1QZ12 (1) 870 aa
    Sequence Information (all 19)
    ORTHOLOGY for pde5ab ( Chr: 7 )
    CITATIONS (20)