ZFIN ID: ZDB-GENE-060815-1
Gene Name: hairy-related 4, tandem duplicate 2
Gene Symbol: her4.2    Nomenclature History

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Previous Names: Hes5d (1), fe18g04 (1), si:ch73-21g5.3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in peripheral nervous system neuron axonogenesis. Predicted to localize to nucleus. Is expressed in several structures, including brain; eye; midbrain neural keel; neural plate; and neural tube. Orthologous to human HES5 (hes family bHLH transcription factor 5).
Genome Resources: Alliance (1),  Gene:100148329 (1), 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1023 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO2-her4 N/A 3
    MO3-her4 N/A 1
    MO4-her4 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH her4.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH her4.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peripheral nervous system neuron axonogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA her4.2-202 (1)    Ensembl 1694
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM her4.2 No data available
    MARKER RELATIONSHIPS
    her4.2 Contained in: [BAC] CH73-21G5 (1)
    her4.2 Contains: [SNP] rs3729486 (1)
    her4.2 Encodes: [EST] cb497 (1) (order this), fe18g04 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001161409 (1)
    Genomic GenBank:CU062502 (1) 62011 nt
    Select Tool
    Polypeptide UniProtKB:B0V3D1 (1) 152 aa
    Sequence Information (all 11)
    ORTHOLOGY for her4.2 ( Chr: 23 )
    CITATIONS (51)