Gene

pdp1

ID
ZDB-GENE-060810-70
Name
pyruvate dehyrogenase phosphatase catalytic subunit 1
Symbol
pdp1 Nomenclature History
Previous Names
  • im:7157162 (1)
  • zgc:174908 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have [pyruvate dehydrogenase (lipoamide)] phosphatase activity and magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in positive regulation of pyruvate dehydrogenase activity and protein dephosphorylation. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Orthologous to human PDP1 (pyruvate dehyrogenase phosphatase catalytic subunit 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pdp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pyruvate decarboxylase deficiency Alliance Pyruvate dehydrogenase phosphatase deficiency 608782
Associated With pdp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000222 PPM-type phosphatase, divalent cation binding
Domain IPR001932 PPM-type phosphatase domain
Family IPR015655 Protein phosphatase 2C family
Homologous_superfamily IPR036457 PPM-type phosphatase domain superfamily
Domain Details Per Protein
Protein Length PPM-type phosphatase, divalent cation binding PPM-type phosphatase domain PPM-type phosphatase domain superfamily Protein phosphatase 2C family
UniProtKB:A9JRU2 519
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations