Gene

itgb1a

ID
ZDB-GENE-060803-2
Name
integrin, beta 1a
Symbol
itgb1a Nomenclature History
Previous Names
  • beta1-1 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Exhibits fibronectin binding activity and protein heterodimerization activity. Predicted to contribute to C-X3-C chemokine binding activity and laminin binding activity. Involved in glial cell development; positive regulation of sprouting angiogenesis; and retina development in camera-type eye. Predicted to localize to cell surface; focal adhesion; and integrin complex. Is expressed in several structures, including cardiovascular system; integument; liver; periderm; and pleuroperitoneal region. Orthologous to human ITGB1 (integrin subunit beta 1).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itgb1a Human Ortholog
No data available
Associated With itgb1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002369 Integrin beta subunit, VWA domain
Domain IPR012896 Integrin beta subunit, tail
Domain IPR013111 EGF-like domain, extracellular
Domain IPR014836 Integrin beta subunit, cytoplasmic domain
Domain IPR016201 PSI domain
Domain IPR040622 Integrin beta, epidermal growth factor-like domain 1
Family IPR015812 Integrin beta subunit
Family IPR027071 Integrin beta-1 subunit
Homologous_superfamily IPR032695 Integrin domain superfamily
Homologous_superfamily IPR036349 Integrin beta tail domain superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain, extracellular Integrin beta-1 subunit Integrin beta, epidermal growth factor-like domain 1 Integrin beta subunit Integrin beta subunit, cytoplasmic domain Integrin beta subunit, tail Integrin beta subunit, VWA domain Integrin beta tail domain superfamily Integrin domain superfamily PSI domain von Willebrand factor A-like domain superfamily
UniProtKB:F1QG85 798
UniProtKB:Q3YAA1 798
UniProtKB:A0A286Y9W0 802
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations