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ZIRC
ZFIN ID: ZDB-GENE-060726-1
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Gene Name: GIPC PDZ domain containing family, member 1
Gene Symbol: gipc1    Nomenclature History

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Previous Names: rgs19ip1 (1), synectin (1), z-synectin (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Exhibits MAP kinase activity. Involved in angiogenesis; artery morphogenesis; and lymphangiogenesis. Is expressed in dorsal aorta; neural tube; posterior cardinal vein; and somite. Orthologous to human GIPC1 (GIPC PDZ domain containing family member 1).
Genome Resources: Alliance (1),  Gene:445568 (1),  Ensembl(GRCz11):ENSDARG00000104483 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40158 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • skt1 Indel Unknown Unknown CRISPR
    skt2 Insertion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-gipc1 1
    MO1-gipc1 N/A 3
    MO2-gipc1 N/A 2
    PHENOTYPE
    Data: 5 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH gipc1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gipc1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Molecular Function MAP kinase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001478 (1)
  • InterPro:IPR017379 (1)
  • InterPro:IPR036034 (1)
  • PROSITE:PS50106 (1)
  • Pfam:PF00595 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gipc1-201 (1)    Ensembl 1296
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gipc1 No data available
    MARKER RELATIONSHIPS
    gipc1 Contained in: [BAC] CH211-120F15 (order this)
    gipc1 Encodes: [cDNA] MGC:194530 (1) (order this), MGC:194545 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004018 (1) 1008 bp
    Select Tool
    Genomic GenBank:BX649515 (1) 153400 bp
    Select Tool
    Polypeptide UniProtKB:Q6B337 (1) 335 aa
    Select Tool
    Sequence Clusters UniGene:114470 (1)
    Sequence Information (all 20)
    ORTHOLOGY for gipc1 ( Chr: 3 )
    CITATIONS (20)