ZFIN is now using GRCz12tu for Genomic Data
Gene
gipc1
- ID
- ZDB-GENE-060726-1
- Name
- GIPC PDZ domain containing family, member 1
- Symbol
- gipc1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables MAP kinase activity. Acts upstream of or within with a positive effect on sprouting angiogenesis. Acts upstream of or within angiogenesis; artery morphogenesis; and lymphangiogenesis. Is expressed in dorsal aorta; neural tube; posterior cardinal vein; and somite. Human ortholog(s) of this gene implicated in oculopharyngodistal myopathy 2. Orthologous to human GIPC1 (GIPC PDZ domain containing family member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| oculopharyngodistal myopathy 2 | Alliance | Oculopharyngodistal myopathy 2 | 618940 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GIPC, GH2 | PDZ domain | PDZ domain-containing protein GIPC1/2/3 | PDZ superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6B337 | InterPro | 335 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers