ZFIN ID: ZDB-GENE-060719-1
Gene Name: leucine aminopeptidase 3
Gene Symbol: lap3    Nomenclature History

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Previous Name: im:7150907

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have aminopeptidase activity; manganese ion binding activity; and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Is expressed in several structures, including alar plate midbrain region; head; immature eye; midbrain; and musculature system. Orthologous to human LAP3 (leucine aminopeptidase 3).
Genome Resources: Alliance (1),  Gene:562854 (1),  Ensembl(GRCz11):ENSDARG00000061981 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12960 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19470 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24839 Point Mutation Unknown Splice Site ENU
    sa31202 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko368a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko368b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-lap3 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lap3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lap3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function aminopeptidase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lap3-201 (1)    Ensembl 2087
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lap3 No data available
    MARKER RELATIONSHIPS
    lap3 Contained in: [BAC] CH211-241E15 (1)
    lap3 Encodes: [EST] IMAGE:7150907 (1), fc55g11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001114847 (1) 2087 nt
    Genomic GenBank:BX901913 (1) 142370 nt
    Select Tool
    Polypeptide UniProtKB:A2BIC6 (1) 517 aa
    Sequence Information (all 9)
    ORTHOLOGY for lap3 ( Chr: 1 )
    CITATIONS (26)