Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-060606-1
Gene Name: cartilage oligomeric matrix protein
Gene Symbol: comp
Previous Names: im:7154332, thbs5 (1), thrombospondin 5 (1), Tsp-4b (1), wu:fb78h09
Location: Chr: 18   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2004 [IMAGE:7154332]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
  head mesenchyme, heart primordium, mesoderm, musculature system (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa12473
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Epiphyseal dysplasia, multiple 1 132400
Pseudoachondroplasia 177170
GENE ONTOLOGY
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component extracellular region (more)
Molecular Function calcium ion binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003367 (1)
  • InterPro:IPR008859 (1)
  • InterPro:IPR008985 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR017897 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR024665 (1)
  • InterPro:IPR028974 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51234 (1)
  • PROSITE:PS51236 (1)
  • Pfam:PF02412 (1)
  • Pfam:PF05735 (1)
  • Pfam:PF07645 (1)
  • Pfam:PF11598 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM comp No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    comp Encodes: [EST] fb78h09, IMAGE:7154332 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:AI558994 502 bp
    Polypeptide UniProtKB:E7FFR1 (1) 749 aa
    Sequence Information (all 6)
    OTHER comp GENE PAGES No links to external sites
    ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish comp 18  
    Human COMP 19 (19p13.1)
  • OMIM:600310
  • Gene:1311
  • Mouse Comp 8 ( 34.15 cM)
  • MGI:88469
  • Gene:12845
  • Orthology Details
    CITATIONS (8)