ZFIN ID: ZDB-GENE-060602-2
Gene Name: pyridoxamine 5'-phosphate oxidase
Gene Symbol: pnpo    Nomenclature History

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Previous Name: im:7138360 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have pyridoxamine-phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Orthologous to human PNPO (pyridoxamine 5'-phosphate oxidase).
Genome Resources: Alliance (1),  Gene:402868 (1),  Ensembl(GRCz11):ENSDARG00000017612 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138360]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35310 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42050 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-pnpo
    1
    CRISPR2-pnpo
    1
    MO1-pnpo N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pnpo HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    pyridoxamine 5'-phosphate oxidase deficiency Alliance Pyridoxamine 5'-phosphate oxidase deficiency 610090
    DISEASE ASSOCIATED WITH pnpo VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function FMN binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pnpo-201 (1)    Ensembl 2155
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pnpo No data available
    MARKER RELATIONSHIPS
    pnpo Contained in: [BAC] CH211-194K22 (1)
    pnpo Encodes: [EST] IMAGE:7138360 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001256178 (1)
    Genomic GenBank:BX248092 (1) 217001 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6PG36 (1) 267 aa
    Sequence Information (all 10)
    ORTHOLOGY for pnpo ( Chr: 12 )
    CITATIONS (22)