Community Action Needed: Please respond to the NIH RFI
Gene

rxfp2l

ID
ZDB-GENE-060531-8
Name
relaxin family peptide receptor 2, like
Symbol
rxfp2l Nomenclature History
Previous Names
  • leugpcr (1)
  • si:ch211-124k10.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in activation of adenylate cyclase activity; adenylate cyclase-activating G protein-coupled receptor signaling pathway; and hormone-mediated signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including brain; liver; oral epithelium; retinal neural layer; and trigeminal ganglion. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human RXFP2 (relaxin family peptide receptor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rxfp2l Human Ortholog
No data available
Associated With rxfp2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR008112 Relaxin receptor
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Repeat IPR026906 BspA type Leucine rich repeat region
Domain Details Per Protein
Protein Length BspA type Leucine rich repeat region GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like LDL receptor-like superfamily Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype Low-density lipoprotein (LDL) receptor class A, conserved site Low-density lipoprotein (LDL) receptor class A repeat Relaxin receptor
UniProtKB:A8BBC5 393
UniProtKB:A0A2R8Q7I1 158
UniProtKB:B0S5B5 692
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations