Gene

lrsam1

ID
ZDB-GENE-060526-97
Name
leucine rich repeat and sterile alpha motif containing 1
Symbol
lrsam1 Nomenclature History
Previous Names
  • si:ch211-208h16.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Is predicted to enable metal ion binding activity. Acts upstream of or within hematopoietic stem cell differentiation and neuron development. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2P. Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lrsam1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease axonal type 2P Alliance Charcot-Marie-Tooth disease, axonal, type 2P 614436
Associated With lrsam1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR001841 Zinc finger, RING-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type
UniProtKB:A0A2R8QM89 714
UniProtKB:A0A0R4IQU4 721
UniProtKB:A2CF42 721
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations