ZFIN ID: ZDB-GENE-060526-74
Gene Name: acetyl-CoA carboxylase alpha
Gene Symbol: acaca    Nomenclature History

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Previous Names: acc (1), fj43d01, im:7138837 (1), si:ch211-199d18.1, wu:fj43d01 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; acetyl-CoA carboxylase activity; and metal ion binding activity. Involved in response to (R)-carnitine. Is expressed in liver and male organism. Orthologous to human ACACA (acetyl-CoA carboxylase alpha).
Genome Resources: Alliance (1),  Gene:559403 (1),  Ensembl(GRCz11):ENSDARG00000078512 (1)
GENE EXPRESSION
All Expression Data: 14 figures from 14 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2214 Point Mutation Unknown Premature Stop ENU
sa20542 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26588 Point Mutation Unknown Premature Stop ENU
    sa33724 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40568 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acaca HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Acetyl-CoA carboxylase deficiency 613933
    DISEASE ASSOCIATED WITH acaca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to (R)-carnitine (more)
    Molecular Function acetyl-CoA carboxylase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acaca-202 (1)    Ensembl 8498
    ncRNA acaca-002 (1)    Ensembl 662
    acaca-003 (1)    Ensembl 514
    acaca-004 (1)    Ensembl 834
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acaca No data available
    MARKER RELATIONSHIPS
    acaca Contained in: [BAC] CH211-199D18 (1), CH211-250O16 (1)
    acaca Encodes: [EST] fj43d01, IMAGE:7138837 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001271308 (1)
    Genomic GenBank:AL935115 (1) 187326 nt
    Select Tool
    Polypeptide UniProtKB:F1QH12 (1) 2390 aa
    Sequence Information (all 51)
    ORTHOLOGY for acaca ( Chr: 5 )
    CITATIONS (78)