ZFIN ID: ZDB-GENE-060526-48
Gene Name: oncostatin M receptor
Gene Symbol: osmr    Nomenclature History

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Previous Name: si:ch211-14b14.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to the external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in primary cutaneous amyloidosis. Orthologous to human OSMR (oncostatin M receptor).
Genome Resources: Alliance (1),  Gene:100144562 (1),  Ensembl(GRCz11):ENSDARG00000100738 (1)
GENE EXPRESSION
All Expression Data: text only from Liongue et al., 2007
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa723 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20340 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20341 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33529 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-osmr N/A 1
    MO2-osmr N/A 1
    DISEASE ASSOCIATED WITH osmr HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    primary cutaneous amyloidosis Alliance Amyloidosis, primary localized cutaneous, 1 105250
    DISEASE ASSOCIATED WITH osmr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function cytokine binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR003961 Fibronectin type III
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Homologous_superfamily IPR036116 Fibronectin type III superfamily
    Domain IPR040817 Leukemia inhibitory factor receptor, D2 domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA osmr-201 (1)    Ensembl 2346
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM osmr No data available
    MARKER RELATIONSHIPS
    osmr Contained in: [BAC] CH211-14B14 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021476733 (1)
    Genomic GenBank:CR318610 (1) 164564 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IJL4 (1) 781 aa
    Sequence Information (all 9)
    ORTHOLOGY for osmr ( Chr: 5 )
    CITATIONS (16)