ZFIN ID: ZDB-GENE-060526-345
Gene Name: piwi-like RNA-mediated gene silencing 2
Gene Symbol: piwil2
Sequence Ontology ID : SO:0000704

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Previous Names: zili (1), sb:eu354, si:dkey-88f5.1

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits piRNA binding activity; involved in several processes, including gamete generation, germ-line stem cell population maintenance, and meiotic cell cycle; localizes to the P granule and  ...
GENE EXPRESSION
All Expression Data: 8 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu354]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2087 Point Mutation Unknown Unknown ENU
hu3173 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • piwil2_unspecified Unspecified Unknown Unknown
    sa18254 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH piwil2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH piwil2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process piRNA metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function piRNA binding (more)
    GO Terms (all 30)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003100 (1)
  • InterPro:IPR003165 (1)
  • InterPro:IPR012337 (1)
  • InterPro:IPR014811 (1)
  • InterPro:IPR036085 (1)
  • InterPro:IPR036397 (1)
  • PROSITE:PS50821 (1)
  • PROSITE:PS50822 (1)
  • Pfam:PF02170 (1)
  • Pfam:PF02171 (1)
  • Pfam:PF08699 (1)
  • EC:3.1.26.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA piwil2-001 (1) 3464
    piwil2-002 (1) 736
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM piwil2 No data available
    MARKER RELATIONSHIPS
    piwil2Contained in: [BAC] DKEY-88F5 (1) (order this)
    piwil2Encodes: [EST] eu354 (1)
    [cDNA] MGC:165340 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080199 (1) 3656bp
    Genomic GenBank:CR450719 (1) 82758bp
    Select Tool
    Polypeptide UniProtKB:T1ECU4 (1) 1087aa
    Sequence Clusters UniGene:40934 (1)
    Sequence Information (all 27)
    OTHER piwil2 GENE PAGES
  • Alliance (1)
  • Gene:572134 (1)
  • VEGA:OTTDARG00000017385 (1)
  • Ensembl(GRCz11):ENSDARG00000062601 (1)
  • ORTHOLOGY for piwil2 (Chr: 5)
    CITATIONS (42)