ZFIN ID: ZDB-GENE-060526-267
Gene Name: G protein-coupled receptor kinase interacting ArfGAP 2a
Gene Symbol: git2a    Nomenclature History

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Previous Names: git2, si:dkey-234h16.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity and metal ion binding activity. Involved in cell migration involved in gastrulation and regulation of cell morphogenesis. Orthologous to human GIT2 (GIT ArfGAP 2).
Genome Resources: Alliance (1),  Gene:793882 (1),  Ensembl(GRCz11):ENSDARG00000061915 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Yu et al., 2011
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024844Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2250 Point Mutation Unknown Premature Stop ENU
    sa33567 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-git2a N/A 1
    MO2-git2a N/A 1
    DISEASE ASSOCIATED WITH git2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH git2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration involved in gastrulation (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA git2a-201 (1)    Ensembl 2938
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM git2a No data available
    MARKER RELATIONSHIPS
    git2a Contained in: [BAC] DKEY-234H16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001126453 (1) 2938 nt
    Genomic GenBank:BX323811 (1) 204094 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A2BG45 (1) 750 aa
    Sequence Information (all 17)
    ORTHOLOGY for git2a ( Chr: 5 )
    CITATIONS (20)