Gene
bmp10
- ID
- ZDB-GENE-060526-211
- Name
- bone morphogenetic protein 10
- Symbol
- bmp10 Nomenclature History
- Previous Names
-
- bmp10b (1)
- si:dkey-13n15.5
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity. Acts upstream of or within artery development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in liver and pericardial region. Used to study hereditary hemorrhagic telangiectasia. Orthologous to human BMP10 (bone morphogenetic protein 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hereditary hemorrhagic telangiectasia | bmp10pt527/pt527; pt505Tg; twu34Tg | control | Capasso et al., 2019 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
| Domain | IPR001111 | TGF-beta, propeptide |
| Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
| Family | IPR015615 | Transforming growth factor-beta-related |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|---|---|
| UniProtKB:A2BGK2 | InterPro | 485 |
Interactions and Pathways
No data available
Plasmids