Gene

antxr2a

ID
ZDB-GENE-060526-14
Name
ANTXR cell adhesion molecule 2a
Symbol
antxr2a Nomenclature History
Previous Names
  • ATR2-a (1)
  • cmg2a (1)
  • si:ch211-116k3.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables actin binding activity and small GTPase binding activity. Acts upstream of or within establishment of mitotic spindle orientation. Located in several cellular components, including cleavage furrow; cortical actin cytoskeleton; and midbody. Is expressed in epiblast. Human ortholog(s) of this gene implicated in fibroma and hyaline fibromatosis syndrome. Orthologous to human ANTXR2 (ANTXR cell adhesion molecule 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Castanon et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Castanon et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With antxr2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hyaline fibromatosis syndrome Alliance Hyaline fibromatosis syndrome 228600
Associated With antxr2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002035 von Willebrand factor, type A
Domain IPR008399 Anthrax toxin receptor, C-terminal
Domain IPR008400 Anthrax toxin receptor, extracellular domain
Family IPR017360 Anthrax toxin receptor
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Domain Details Per Protein
Protein Length Anthrax toxin receptor Anthrax toxin receptor, C-terminal Anthrax toxin receptor, extracellular domain von Willebrand factor A-like domain superfamily von Willebrand factor, type A
UniProtKB:Q19VG7 478
UniProtKB:A0A0R4ICZ6 500
UniProtKB:A4QP34 478
UniProtKB:A0A2R8QHK0 490
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations