ZFIN ID: ZDB-GENE-060526-14
Gene Name: anthrax toxin receptor 2a
Gene Symbol: antxr2a

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Previous Names: ATR2-a (1), cmg2a (1), si:ch211-116k3.1

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Castanon et al., 2012
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Gastrula:Bud (10.0h-10.33h)
  epiblast cell cortex, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8427 Point Mutation Unknown Premature Stop ENU
sa15951 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-antxr2a (1), MO2-antxr2a (1), MO3-antxr2a (1), MO4-antxr2a (1)
    PHENOTYPE
    Data: 4 figures from Castanon et al., 2012
    Observed in: anterior neural plate, convergent extension, epiblast actin cap, epiblast mitotic spindle (all 8) expand
    DISEASE ASSOCIATED WITH antxr2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Hyaline fibromatosis syndrome 228600
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process establishment of mitotic spindle orientation (more)
    Cellular Component cleavage furrow (more)
    Molecular Function Rho GTPase binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002035 (1)
  • InterPro:IPR008399 (1)
  • InterPro:IPR008400 (1)
  • InterPro:IPR017360 (1)
  • PROSITE:PS50234 (1)
  • Pfam:PF00092 (1)
  • Pfam:PF05586 (1)
  • Pfam:PF05587 (1)
  •  Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM antxr2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    antxr2aContained in: [BAC] CH211-116K3 (1) (order this), DKEY-183O11 (order this)
    antxr2aEncodes: [cDNA] MGC:162808 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044709 (1) 2117bp
    Genomic GenBank:BX629340 172090bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ICZ6 (1) 478aa
    Sequence Clusters UniGene:12251 (1)
    Sequence Information (all 18)
    OTHER antxr2a GENE PAGES
  • Gene:557239 (1)
  • Ensembl(GRCz10):ENSDARG00000104118 (1)
  • ORTHOLOGY for antxr2a (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human ANTXR2 4
  • Gene:118429
  • OMIM:608041
  • HGNC:21732
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Antxr2 5
  • MGI:1919164
  • Gene:71914
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)