Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-060526-14
Gene Name: anthrax toxin receptor 2a
Gene Symbol: antxr2a
Previous Names: ATR2-a (1), cmg2a (1), si:ch211-116k3.1
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Castanon et al., 2012
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Gastrula:Bud (10.0h-10.33h)
  epiblast cell cortex, whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa15951
Knockdown reagents: MO1-antxr2a (1), MO2-antxr2a (1), MO3-antxr2a (1), MO4-antxr2a (1)
PHENOTYPE
Data: 4 figures from Castanon et al., 2012
Observed in: anterior neural plate, convergent extension, epiblast actin cap, epiblast mitotic spindle (all 8) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Hyaline fibromatosis syndrome 228600
GENE ONTOLOGY
Ontology GO Term
Biological Process establishment of mitotic spindle orientation (more)
Cellular Component cleavage furrow (more)
Molecular Function Rho GTPase binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002035 (1)
  • InterPro:IPR008399 (1)
  • InterPro:IPR008400 (1)
  • InterPro:IPR017360 (1)
  • PROSITE:PS50234 (1)
  • Pfam:PF00092 (1)
  • Pfam:PF05586 (1)
  • Pfam:PF05587 (1)
  •  Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM antxr2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    antxr2a Contained in: [BAC] CH211-116K3 (1) (order this), DKEY-183O11
    antxr2a Encodes: [cDNA] MGC:162808 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044709 (1) 2117 bp
    Genomic GenBank:BX629340 172090 bp
    Select Tool
    Polypeptide UniProtKB:A4QP34 (1) 478 aa
    Sequence Clusters UniGene:12251 (1)
    Sequence Information (all 18)
    OTHER antxr2a GENE PAGES
  • Gene:557239 (1)
  • Ensembl(Zv9):ENSDARG00000060520 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish antxr2a 5  
    Human ANTXR2 4 (4q21.21)
  • OMIM:608041
  • Gene:118429
  • Mouse Antxr2 5 ( 47.77 cM)
  • MGI:1919164
  • Gene:71914
  • Orthology Details
    CITATIONS (17)