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Gene

usp22

ID
ZDB-GENE-060512-211
Name
ubiquitin specific peptidase 22
Symbol
usp22 Nomenclature History
Previous Names
  • zgc:136342
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable thiol-dependent deubiquitinase and zinc ion binding activity. Predicted to act upstream of or within chromatin organization; protein deubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 105. Orthologous to several human genes including USP22 (ubiquitin specific peptidase 22).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tse et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp22 Human Ortholog
No data available
Associated With usp22 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR001607 Zinc finger, UBP-type
Domain IPR028889 Ubiquitin specific protease domain
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase Ubiquitin specific protease, conserved site Ubiquitin specific protease domain Zinc finger, RING/FYVE/PHD-type Zinc finger, UBP-type
UniProtKB:F1QXG0 466
UniProtKB:A6H8I0 506
UniProtKB:Q502D6 265
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations