Gene
fancc
- ID
- ZDB-GENE-060510-2
- Name
- FA complementation group C
- Symbol
- fancc Nomenclature History
- Previous Names
-
- zgc:154105
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be involved in cellular response to oxidative stress and nucleotide-excision repair. Predicted to localize to Fanconi anaemia nuclear complex. Is expressed in intermediate cell mass of mesoderm and nervous system. Human ortholog(s) of this gene implicated in Fanconi anemia (multiple); acute myeloid leukemia; breast cancer; pancreatic cancer; and pancytopenia. Orthologous to human FANCC (FA complementation group C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ramanagoudr-Bhojappa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group C | Alliance | Fanconi anemia, complementation group C | 227645 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000686 | Fanconi anaemia group C protein |
Domain Details Per Protein
| Protein | Length | Fanconi anaemia group C protein |
|---|---|---|
|
UniProtKB:Q1X872
|
518 | |
|
UniProtKB:B0V1A8
|
518 | |
|
UniProtKB:B0V1A9
|
554 |
Interactions and Pathways
No data available
Plasmids
No data available