ZFIN ID: ZDB-GENE-060503-934
Gene Name: neuronal PAS domain protein 1
Gene Symbol: npas1    Nomenclature History

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Previous Names: npas3b, si:dkeyp-13e2.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Orthologous to human NPAS1 (neuronal PAS domain protein 1).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000015876 (2)
Note: The nomenclature for this gene has been updated (September 2016) to npas1 as supported by AA alignment, synteny and phylogenetic tree data.
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019512Tg Transgenic Insertion Unknown Unknown DNA
la019513Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027667Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45530 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH npas1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH npas1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function protein dimerization activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000014 PAS domain
    Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
    Domain IPR013655 PAS fold-3
    Domain IPR013767 PAS fold
    Homologous_superfamily IPR035965 PAS domain superfamily
    Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA npas1-201 (1)    Ensembl 5128
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM npas1 No data available
    MARKER RELATIONSHIPS
    npas1 Contained in: [BAC] DKEYP-13E2 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:BX296539 (1) 135623 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q2I0 (1) 770 aa
    Sequence Information (all 4)
    ORTHOLOGY for npas1 ( Chr: 15 )
    CITATIONS (21)