Gene
slc9a3.2
- ID
- ZDB-GENE-060503-640
- Name
- solute carrier family 9 member A3, tandem duplicate 2
- Symbol
- slc9a3.2 Nomenclature History
- Previous Names
-
- nhe3b (1)
- si:dkey-3n22.6
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Exhibits sodium:proton antiporter activity. Involved in ammonium transmembrane transport; sodium ion homeostasis; and sodium ion import across plasma membrane. Localizes to apical plasma membrane. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8. Is expressed in gill; integument; and renal system. Orthologous to human SLC9A3 (solute carrier family 9 member A3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital secretory sodium diarrhea 8 | Alliance | Diarrhea 8, secretory sodium, congenital | 616868 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cation/H+ exchanger | Cation/H+ exchanger, CPA1 family | Na+/H+ exchanger | Na+/H+ exchanger, isoforms 3/5 |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M3ASE1
|
845 | ||||
|
UniProtKB:A9XP97
|
851 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
slc9a3.2-201
(1)
|
Havana | 2796 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-slc9a3.2 | polyclonal | Rat |
|
2 | |||
| Ab2-slc9a3.2 | polyclonal | Rabbit |
|
1 | |||
| Ab4-slc9a3.2 | Rabbit |
|
2 |
Plasmids
No data available