Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-060503-585
Gene Name: solute carrier family 5 (sodium iodide symporter), member 5
Gene Symbol: slc5a5
Previous Names: NIS (1), si:ch211-200a16.4
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  thyroid follicle, thyroid primordium
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Thyroid dyshormonogenesis 1 274400
GENE ONTOLOGY
Ontology GO Term
Biological Process transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function transporter activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001734 (1)
  • InterPro:IPR019900 (1)
  • PROSITE:PS50283 (1)
  • Pfam:PF00474 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc5a5-001 (1) 1698
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM slc5a5 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slc5a5 Contained in: [BAC] CH211-200A16 (1) (order this)
    slc5a5 Encodes: [cDNA] MGC:162275 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089391 (1) 2056 bp
    Genomic GenBank:BX119975 (1) 154904 bp
    Select Tool
    Polypeptide UniProtKB:A4IG60 (1) 601 aa
    Sequence Clusters UniGene:100996 (1)
    Sequence Information (all 18)
    OTHER slc5a5 GENE PAGES
  • Gene:561445 (1)
  • VEGA:OTTDARG00000006581 (1)
  • Ensembl(Zv9):ENSDARG00000005392 (1)
  • MAPPING INFORMATION
    Chr: 8 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish slc5a5 8  
    Human SLC5A5 19 (19p13.11)
  • OMIM:601843
  • Gene:6528
  • Mouse Slc5a5 8 ( 34.36 cM)
  • MGI:2149330
  • Gene:114479
  • CITATIONS (30)