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General Information
ZIRC
ZFIN ID: ZDB-GENE-060503-585
Gene Name: solute carrier family 5 member 5
Gene Symbol: slc5a5
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: NIS (1), si:ch211-200a16.4

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sodium:iodide symporter activity. Predicted to be involved in iodide transport; thyroid hormone generation; and transmembrane transport. Predicted to localize to the integral  ...
GENE EXPRESSION
All Expression Data: 16 figures from 8 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc5a5 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Thyroid dyshormonogenesis 1 274400
DISEASE ASSOCIATED WITH slc5a5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function transmembrane transporter activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001734 (1)
  • InterPro:IPR038377 (1)
  • PROSITE:PS50283 (1)
  • Pfam:PF00474 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc5a5-201 (1) 1698
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc5a5 No data available
    MARKER RELATIONSHIPS
    slc5a5 Contained in: [BAC] CH211-200A16 (1) (order this)
    slc5a5 Encodes: [cDNA] MGC:162275 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089391 (1) 2056 bp
    Genomic GenBank:BX119975 (1) 154904 bp
    Select Tool
    Polypeptide UniProtKB:A4IG60 (1) 601 aa
    Sequence Clusters UniGene:100996 (1)
    Sequence Information (all 19)
    ORTHOLOGY for slc5a5 ( Chr: 8 )
    CITATIONS (69)