ZFIN ID: ZDB-GENE-060503-585
Gene Name: solute carrier family 5 (sodium/iodide cotransporter), member 5
Gene Symbol: slc5a5
Previous Names: NIS (1), si:ch211-200a16.4
Location: Chr: 8 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  thyroid follicle, thyroid primordium
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc5a5 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital hypothyroidism Thyroid dyshormonogenesis 1 274400
GENE ONTOLOGY
Ontology GO Term
Biological Process transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function transporter activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001734 (1)
  • InterPro:IPR019900 (1)
  • PROSITE:PS50283 (1)
  • Pfam:PF00474 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc5a5-001 (1) 1698
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM slc5a5 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slc5a5Contained in: [BAC] CH211-200A16 (1) (order this)
    slc5a5Encodes: [cDNA] MGC:162275 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089391 (1) 2056bp
    Genomic GenBank:BX119975 (1) 154904bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ICT1 (1) 601aa
    Sequence Clusters UniGene:100996 (1)
    Sequence Information (all 18)
    OTHER slc5a5 GENE PAGES
  • Gene:561445 (1)
  • VEGA:OTTDARG00000006581 (1)
  • Ensembl(GRCz10):ENSDARG00000005392 (1)
  • ORTHOLOGY for slc5a5 (Chr: 8)
    Species Symbol Chromosome Accession # Evidence
    Human SLC5A5 19
  • Gene:6528
  • OMIM:601843
  • HGNC:11040
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Mouse Slc5a5 8
  • MGI:2149330
  • Gene:114479
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (34)