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ZIRC
ZFIN ID: ZDB-GENE-060503-575
Gene Name: valyl-tRNA synthetase 2, mitochondrial
Gene Symbol: vars2    Nomenclature History

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Previous Name: si:ch211-152p11.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have valine-tRNA ligase activity. Predicted to be involved in valyl-tRNA aminoacylation. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human VARS2 (valyl-tRNA synthetase 2, mitochondrial).
Genome Resources: Alliance (1),  Gene:100170827 (1),  Ensembl(GRCz11):ENSDARG00000056717 (2)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH vars2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 20 Alliance Combined oxidative phosphorylation deficiency 20 615917
DISEASE ASSOCIATED WITH vars2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process translation (more)
Cellular Component cytosol (more)
Molecular Function aminoacyl-tRNA editing activity (more)
GO Terms (all 10)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA vars2-201 (1)    Ensembl 3522
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM vars2 No data available
MARKER RELATIONSHIPS
vars2 Contained in: [BAC] CH73-25F10 (1) (order this), CH73-337N6 (1) (order this), CH211-152P11 (1) (order this)
vars2 Encodes: [cDNA] MGC:194532 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001130661 (1) 3502 bp
Genomic GenBank:BX511233 (1) 193921 bp
Select Tool
Polypeptide UniProtKB:B3DIT4 (1) 1057 aa
Sequence Clusters UniGene:89026 (1)
Sequence Information (all 16)
ORTHOLOGY for vars2 ( Chr: 19 )
CITATIONS (18)