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General Information
ZIRC
ZFIN ID: ZDB-GENE-060503-458
Gene Name: protein tyrosine phosphatase non-receptor type 22
Gene Symbol: ptpn22
Sequence Ontology ID : SO:0001217

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Previous Name: si:dkey-78k11.1

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Human ortholog(s) of this gene implicated in several diseases, including Addison's  ...
GENE EXPRESSION
All Expression Data: Fig. 4 from van Eekelen et al., 2010
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ptpn22 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
rheumatoid arthritis {Rheumatoid arthritis, susceptibility to} 180300
systemic lupus erythematosus {Systemic lupus erythematosus susceptibility to} 152700
type 1 diabetes mellitus {Diabetes, type 1, susceptibility to} 222100
DISEASE ASSOCIATED WITH ptpn22 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dephosphorylation (more)
Molecular Function hydrolase activity (more)
GO Terms (all 6)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA ptpn22-202 (1) 585
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ptpn22 No data available
MARKER RELATIONSHIPS
ptpn22 Contained in: [BAC] DKEY-78K11 (1) (order this)
ptpn22 Encodes: [cDNA] MGC:162702 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001099420 (1) 3187 bp
Genomic GenBank:AL845287 (1) 174301 bp
Select Tool
Polypeptide UniProtKB:A0A0R4IER5 (1) 887 aa
Sequence Clusters UniGene:88698 (1)
Sequence Information (all 22)
ORTHOLOGY for ptpn22 ( Chr: 23 )
CITATIONS (18)