tecpr2

ID

ZDB-GENE-060503-358

Name

tectonin beta-propeller repeat containing 2

Symbol

tecpr2 Nomenclature History

Previous Names

si:dkey-46n18.5 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be involved in protein exit from endoplasmic reticulum. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 49. Orthologous to human TECPR2 (tectonin beta-propeller repeat containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Paul et al., 2025

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Paul et al., 2025
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tecpr2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spastic paraplegia 49	Alliance	Neuropathy, hereditary sensory and autonomic, type IX, with developmental delay	615031

Associated With tecpr2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR056499	HPS5-like, beta-propeller domain
Homologous_superfamily	IPR009091	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR006624	Beta-propeller repeat TECPR