ZFIN ID: ZDB-GENE-060503-16
Gene Name: DENN/MADD domain containing 1B
Gene Symbol: dennd1b    Nomenclature History

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Previous Name: si:ch211-195i21.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have Rab guanyl-nucleotide exchange factor activity and phosphatidylinositol phosphate binding activity. Predicted to be involved in endocytic recycling and endocytosis. Predicted to localize to the cytosol and intracellular membrane-bounded organelle. Is expressed in forebrain and hypothalamus. Orthologous to human DENND1B (DENN domain containing 1B).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000101868 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43850 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dennd1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dennd1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endocytic recycling (more)
    Cellular Component cytosol (more)
    Molecular Function Rab guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001194 cDENN domain
    Domain IPR005112 dDENN domain
    Domain IPR005113 uDENN domain
    Domain IPR037516 Tripartite DENN domain
    Family IPR040032 DENN domain-containing protein 1A/1B/1C
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dennd1b-201 (1)    Ensembl 2317
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dennd1b No data available
    MARKER RELATIONSHIPS
    dennd1b Contained in: [BAC] CH73-189A7 (1), CH211-195I21 (1), DKEY-114D20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:CR388178 (1) 171742 bp
    Select Tool
    Polypeptide UniProtKB:F1QH29 (1) 468 aa
    Sequence Information (all 7)
    ORTHOLOGY for dennd1b ( Chr: 22 )
    CITATIONS (15)