Gene

pold1

ID
ZDB-GENE-060429-1
Name
polymerase (DNA directed), delta 1, catalytic subunit
Symbol
pold1 Nomenclature History
Previous Names
  • fla
  • flat head
  • im:7139126
  • zgc:152688
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have 3'-5'-exodeoxyribonuclease activity and DNA-directed DNA polymerase activity. Involved in DNA replication. Predicted to localize to delta DNA polymerase complex. Is expressed in several structures, including brain; immature eye; neural crest; proliferative region; and retina. Orthologous to human POLD1 (DNA polymerase delta 1, catalytic subunit).
Genome Resources
Note
None
Expression
All Expression Data
14 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pold1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome 615381
{Colorectal cancer, susceptibility to, 10} 612591
Associated With pold1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017964 DNA-directed DNA polymerase, family B, conserved site
Domain IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain
Domain IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain
Domain IPR025687 C4-type zinc-finger of DNA polymerase delta
Family IPR006172 DNA-directed DNA polymerase, family B
Homologous_superfamily IPR012337 Ribonuclease H-like superfamily
Homologous_superfamily IPR023211 DNA polymerase, palm domain superfamily
Homologous_superfamily IPR036397 Ribonuclease H superfamily
Homologous_superfamily IPR042087 DNA polymerase family B, C-terminal domain
Homologous_superfamily IPR043502 DNA/RNA polymerase superfamily
Domain Details Per Protein
Protein Length C4-type zinc-finger of DNA polymerase delta DNA-directed DNA polymerase, family B DNA-directed DNA polymerase, family B, conserved site DNA-directed DNA polymerase, family B, exonuclease domain DNA-directed DNA polymerase, family B, multifunctional domain DNA polymerase family B, C-terminal domain DNA polymerase, palm domain superfamily DNA/RNA polymerase superfamily Ribonuclease H-like superfamily Ribonuclease H superfamily
UniProtKB:Q2KNE0 1105
UniProtKB:B3DKJ9 1105
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations