ZFIN ID: ZDB-GENE-060429-1
Gene Name: polymerase (DNA directed), delta 1, catalytic subunit
Gene Symbol: pold1
Sequence Ontology ID : SO:0000704

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Previous Names: fla, flat head, im:7139126, zgc:152688

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 2 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [IMAGE:7139126]
  6 figures (6 images) from Thisse et al., 2004 [IMAGE:7160082]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  brain, ciliary marginal zone, digestive system, immature eye (all 12) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12879 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17444 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18749 Point Mutation Unknown Splice Site ENU
    ta53c Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf21c Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • th5b Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tu255e Unknown Unknown Unknown ENU
    ty76 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 12 figures from 3 publications
    Observed in: brain, ceratobranchial 5 bone, ceratobranchial 5 tooth, ceratohyal cartilage (all 22) expand
    DISEASE ASSOCIATED WITH pold1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Colorectal cancer, susceptibility to, 10} 612591
    Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome 615381
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA replication (more)
    Cellular Component nucleus (more)
    Molecular Function 3'-5' exonuclease activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006133 (1)
  • InterPro:IPR006134 (1)
  • InterPro:IPR006172 (1)
  • InterPro:IPR012337 (1)
  • InterPro:IPR017964 (1)
  • InterPro:IPR023211 (1)
  • InterPro:IPR025687 (1)
  • InterPro:IPR036397 (1)
  • PROSITE:PS00116 (1)
  • Pfam:PF00136 (1)
  • Pfam:PF03104 (1)
  • Pfam:PF14260 (1)
  • EC:2.7.7.7 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pold1-002 (1) 3561
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pold1 No data available
    MARKER RELATIONSHIPS
    pold1Contained in: [BAC] DKEY-29B22 (1) (order this), DKEY-30J10 (1) (order this)
    pold1Encodes: [EST] IMAGE:7139126 (1) (order this), IMAGE:7160082 (1) (order this)
    [cDNA] MGC:152688 (1), MGC:195302 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039810 (1) 3562bp
    Genomic GenBank:CR847509 (1) 157983bp
    Select Tool
    Polypeptide UniProtKB:B3DKJ9 (1) 1105aa
    Sequence Clusters UniGene:49022 (1)
    Sequence Information (all 18)
    OTHER pold1 GENE PAGES
  • Alliance (1)
  • Gene:556456 (1)
  • VEGA:OTTDARG00000019271 (1)
  • Ensembl(GRCz10):ENSDARG00000027689 (1)
  • ORTHOLOGY for pold1 (Chr: 3)
    CITATIONS (32)