ZFIN ID: ZDB-GENE-060421-7091
Gene Name: F-box protein 8
Gene Symbol: fbxo8    Nomenclature History

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Previous Name: zgc:136842

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is expressed in female organism. Orthologous to human FBXO8 (F-box protein 8).
Genome Resources: Alliance (1),  Gene:678549 (1),  Ensembl(GRCz11):ENSDARG00000007477 (2)
GENE EXPRESSION
All Expression Data: Table S1 from Newman et al., 2019
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13814 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fbxo8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fbxo8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of ARF protein signal transduction (more)
    Molecular Function ARF guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fbxo8-201 (1)    Ensembl 1815
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fbxo8 No data available
    MARKER RELATIONSHIPS
    fbxo8 Contained in: [BAC] CH73-317E19 (1)
    fbxo8 Encodes: [cDNA] MGC:136842 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001040307 (1) 1805 nt
    Genomic GenBank:BX000460 (1) 173084 nt
    Select Tool
    Polypeptide UniProtKB:Q1RLU2 (1) 323 aa
    Sequence Information (all 12)
    ORTHOLOGY for fbxo8 ( Chr: 1 )
    CITATIONS (18)