ZFIN ID: ZDB-GENE-060312-41
Gene Name: Usher syndrome 1C
Gene Symbol: ush1c
Sequence Ontology ID : SO:0000704

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Previous Names: harmonin, zgc:136806

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  anterior crista, anterior macula, brain, hair cell (all 21) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh293 Point Mutation Exon 5 Premature Stop ENU
sa9749 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24680 Point Mutation Unknown Splice Site, Nonsynonymous ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39483 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: CRISPR1-ush1c (1), CRISPR2-ush1c (2), CRISPR3-ush1c (2), MO1-ush1c (1), MO2-ush1c (1)
    PHENOTYPE
    Data: 6 figures from 2 publications
    Observed in: anterior macula stereocilium bundle, auditory receptor cell kinocilium, auditory receptor cell stereocilium bundle, detection of light stimulus involved in visual perception (all 14) expand
    DISEASE ASSOCIATED WITH ush1c HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive nonsyndromic deafness 18A Deafness, autosomal recessive 18A 602092
    Usher syndrome type 1C Usher syndrome, type 1C 276904
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inner ear receptor stereocilium organization (more)
    Cellular Component cellular_component (more)
    Molecular Function protein binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001478 (1)
  • InterPro:IPR030237 (1)
  • PROSITE:PS50106 (1)
  • Pfam:PF00595 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ush1c-001 (1) 1915
    ush1c-002 (1) 975
    ush1c-003 (1) 977
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-ush1c (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ush1c No data available
    MARKER RELATIONSHIPS
    ush1cContained in: [BAC] DKEY-4M3 (1) (order this)
    ush1cEncodes: [cDNA] MGC:136806 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039929 (1) 1944bp
    Genomic GenBank:CR855275 (1) 159960bp
    Select Tool
    Polypeptide UniProtKB:Q29RC0 (1) 548aa
    Sequence Clusters UniGene:80034 (1)
    Sequence Information (all 21)
    OTHER ush1c GENE PAGES
  • Alliance (1)
  • Gene:564412 (1)
  • VEGA:OTTDARG00000028424 (1)
  • Ensembl(GRCz10):ENSDARG00000051876 (1)
  • ORTHOLOGY for ush1c (Chr: 25)
    CITATIONS (19)