Gene

plag1

ID
ZDB-GENE-060302-2
Name
pleiomorphic adenoma gene 1
Symbol
plag1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Is expressed in several structures, including axial vasculature; head; head mesenchyme; immature eye; and ventricular zone. Human ortholog(s) of this gene implicated in Silver-Russell syndrome and pleomorphic adenoma. Orthologous to human PLAG1 (PLAG1 zinc finger).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Pendeville et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plag1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pleomorphic adenoma Alliance Adenomas, salivary gland pleomorphic, somatic 181030
Silver-Russell syndrome 4 618907
Associated With plag1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR027765 Zinc finger protein PLAG1/PLAGL2
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type Zinc finger protein PLAG1/PLAGL2
UniProtKB:Q29YB2 393
UniProtKB:Q08CU9 393
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations