Gene

plag1

ID
ZDB-GENE-060302-2
Name
pleiomorphic adenoma gene 1
Symbol
plag1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nuclear chromatin. Is expressed in several structures, including axial vasculature; head; head mesenchyme; immature eye; and ventricular zone. Human ortholog(s) of this gene implicated in Silver-Russell syndrome and pleomorphic adenoma. Orthologous to human PLAG1 (PLAG1 zinc finger).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Pendeville et al., 2006
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plag1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pleomorphic adenoma Alliance Adenomas, salivary gland pleomorphic, somatic 181030
Silver-Russell syndrome 4 618907
Associated With plag1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR027765 Zinc finger protein PLAG1/PLAGL2
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type Zinc finger protein PLAG1/PLAGL2
UniProtKB:Q29YB2 393
UniProtKB:Q08CU9 393
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations