ZFIN ID: ZDB-GENE-060228-5
Gene Name: connector enhancer of kinase suppressor of Ras 2a
Gene Symbol: cnksr2a    Nomenclature History

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Previous Name: cnksr2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to be involved in regulation of signal transduction. Predicted to localize to cytoplasm and membrane. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Orthologous to human CNKSR2 (connector enhancer of kinase suppressor of Ras 2).
Genome Resources: Alliance (1),  Gene:561623 (1),  Ensembl(GRCz11):ENSDARG00000074480 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a355 Small Deletion Unknown Unknown CRISPR
la014556Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014557Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022941Tg Transgenic Insertion Unknown Unknown DNA
    sa6772 Point Mutation Unknown Premature Stop ENU
    sa37902 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37903 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45832 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cnksr2a 1
    CRISPR2-cnksr2a 1
    CRISPR3-cnksr2a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cnksr2a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    syndromic X-linked mental retardation Hough type Alliance Mental retardation, X-linked, syndromic, Houge type 301008
    DISEASE ASSOCIATED WITH cnksr2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of signal transduction (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cnksr2a-202 (1)    Ensembl 2050
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cnksr2a No data available
    MARKER RELATIONSHIPS
    cnksr2a Contained in: [BAC] CH211-118O21 (1), DKEYP-121E10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009297460 (1)
    Genomic GenBank:BX571698 (1) 168886 nt
    Select Tool
    Polypeptide UniProtKB:E7F641 (1) 1018 aa
    Sequence Information (all 25)
    ORTHOLOGY for cnksr2a ( Chr: 24 )
    CITATIONS (20)