ZFIN ID: ZDB-GENE-060222-1
Gene Name: prostaglandin E receptor 4 (subtype EP4) a
Gene Symbol: ptger4a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: ep4 (1), ep4a (1), PRS4 (1), ptger4l

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits prostaglandin E receptor activity. Involved in animal organ development and cell migration involved in gastrulation. Predicted to localize to plasma membrane. Is expressed in several structures, including digestive system; gonad; hematopoietic stem cell; immune system; and mesoderm. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; and ulcerative colitis. Orthologous to human PTGER4 (prostaglandin E receptor 4).
Genome Resources: Alliance (1),  Gene:562469 (1),  Ensembl(GRCz11):ENSDARG00000059236 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa56 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44679 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ptger4a N/A 4
    MO2-ptger4a N/A 7
    MO3-ptger4a N/A 1
    MO4-ptger4a N/A 1
    MO5-ptger4a N/A 1
    DISEASE ASSOCIATED WITH ptger4a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ptger4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic liver development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function prostaglandin E receptor activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ptger4a-201 (1)    Ensembl 1352
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ptger4a No data available
    MARKER RELATIONSHIPS
    ptger4a Contained in: [BAC] CH211-14C17 (1)
    ptger4a Encodes: [cDNA] MGC:158112 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001039629 (1) 1362 nt
    Genomic GenBank:CT027631 (1) 194262 nt
    Select Tool
    Polypeptide UniProtKB:A0PJP9 (1) 403 aa
    Sequence Information (all 11)
    ORTHOLOGY for ptger4a ( Chr: 8 )
    CITATIONS (36)