ZFIN ID: ZDB-GENE-060216-2
Gene Name: norrin cystine knot growth factor NDP
Gene Symbol: ndp
Sequence Ontology ID : SO:0000704

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Previous Name: si:ch211-222m21.5

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity; involved in retina vasculature development in camera-type eye; predicted to localize to the extracellular space; orthologous to human NDP (NDP, norrin cystine  ...
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41464 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 3 from Wu et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH ndp HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    exudative vitreoretinopathy Exudative vitreoretinopathy 2, X-linked 305390
    Norrie disease Norrie disease 310600
    DISEASE ASSOCIATED WITH ndp VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process retina vasculature development in camera-type eye (more)
    Cellular Component extracellular region (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003064 (1)
  • InterPro:IPR004133 (1)
  • InterPro:IPR006207 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS01185 (1)
  • PROSITE:PS01225 (1)
  • Pfam:PF03045 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ndp-001 (1) 811
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ndp No data available
    MARKER RELATIONSHIPS
    ndpContained in: [BAC] CH211-222M21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021478990 (1)
    Genomic GenBank:BX572627 (1) 209758bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7F073 (1) 138aa
    Sequence Clusters UniGene:76577 (1)
    Sequence Information (all 8)
    OTHER ndp GENE PAGES
  • Alliance (1)
  • Gene:100003793 (1)
  • VEGA:OTTDARG00000035032 (1)
  • Ensembl(GRCz11):ENSDARG00000076569 (1)
  • ORTHOLOGY for ndp (Chr: 9)
    CITATIONS (14)