ZFIN ID: ZDB-GENE-060201-1
Gene Name: ATP synthase F1 subunit alpha
Gene Symbol: atp5fa1    Nomenclature History

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Previous Names: atp5a1, zgc:154103

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to contribute to ATPase activity. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to localize to plasma membrane and proton-transporting ATP synthase complex, catalytic core F(1). Is expressed in brain; male organism; myotome; pectoral fin; and pharyngeal arch 3-7. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 22 and mitochondrial complex V (ATP synthase) deficiency nuclear type 4. Orthologous to human ATP5F1A (ATP synthase F1 subunit alpha).
Genome Resources: Alliance (1),  Gene:553755 (1),  Ensembl(GRCz11):ENSDARG00000010149 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-atp5fa1 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH atp5fa1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 22 Alliance ?Combined oxidative phosphorylation deficiency 22 616045
mitochondrial complex V (ATP synthase) deficiency nuclear type 4 Alliance ?Mitochondrial complex V (ATP synthase) deficiency, nuclear type 4 615228
DISEASE ASSOCIATED WITH atp5fa1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ATP biosynthetic process (more)
Cellular Component proton-transporting ATP synthase complex, catalytic core F(1) (more)
Molecular Function adenyl ribonucleotide binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atp5fa1-201 (1)    Ensembl 1883
ncRNA atp5a1-002 (1)    Ensembl 440
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-atp5a1 monoclonal IgG2b , k Mouse WB MitoSciences
3
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atp5fa1 No data available
MARKER RELATIONSHIPS
atp5fa1 Contained in: [BAC] CH73-314K14 (1)
atp5fa1 Encodes: [cDNA] MGC:154103 (1)
atp5fa1 Has Artifact: [cDNA] MGC:56505
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001077355 (1)
Genomic GenBank:CU466288 (1) 93071 nt
Select Tool
Polypeptide UniProtKB:Q08BA1 (1) 551 aa
Sequence Information (all 15)
ORTHOLOGY for atp5fa1 ( Chr: 21 )
CITATIONS (44)