ZFIN ID: ZDB-GENE-060131-1
Gene Name: androgen receptor
Gene Symbol: ar
Previous Names: Ar beta (1), AR-A (1), NR3C4 (1)
Location: Chr: 5 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 18 figures from 6 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2008 [ay510448]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, caudal periventricular hypothalamus, dorsal periventricular hypothalamus, eye (all 35) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa20472 Point Mutation ENU
Targeting reagents: MO1-ar (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ar HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
androgen insensitivity syndrome Androgen insensitivity 300068
hypospadias Hypospadias 1, X-linked 300633
Kennedy's disease Spinal and bulbar muscular atrophy of Kennedy 313200
prostate cancer {Prostate cancer, susceptibility to} 176807
Androgen insensitivity, partial, with or without breast cancer 312300
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function RNA polymerase II transcription factor activity, sequence-specific DNA binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000536 (1)
  • InterPro:IPR001628 (1)
  • InterPro:IPR001723 (1)
  • InterPro:IPR013088 (1)
  • PROSITE:PS00031 (1)
  • PROSITE:PS51030 (1)
  • Pfam:PF00104 (1)
  • Pfam:PF00105 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ar-001 (1) 3177
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ar No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arContained in: [BAC] CH211-194G1 (1) (order this), DKEY-71K8 (1) (order this)
    arEncodes: [EST] ay510448 (1) (order this), fa25e03 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001083123 (1) 5300bp
    Genomic GenBank:CR396593 (1) 197143bp
    Select Tool
    Polypeptide UniProtKB:B9P3Q7 (1) 869aa
    Sequence Clusters UniGene:75914 (1)
    Sequence Information (all 30)
    OTHER ar GENE PAGES
  • Gene:100005148 (1)
  • VEGA:OTTDARG00000017972 (1)
  • Ensembl(GRCz10):ENSDARG00000067976 (1)
  • ORTHOLOGY for ar (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human AR X
  • Gene:367
  • OMIM:313700
  • HGNC:644
  • Amino acid sequence comparison (6)
    Conserved genome location (synteny) (2)
    Nucleotide sequence comparison (1)
    Phylogenetic tree (1)
    Mouse Ar X
  • MGI:88064
  • Gene:11835
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (1)
    Phylogenetic tree (1)
    Download Curated Orthology
    CITATIONS (70)