ZFIN ID: ZDB-GENE-060126-7
Gene Name: aryl hydrocarbon receptor nuclear translocator
Gene Symbol: arnt    Nomenclature History

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Previous Names: ARNT1 (1), zfARNT1a (1), zfARNT1b (1), zfARNT1c (1), zgc:136664

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in positive regulation of transcription, DNA-templated; response to toxic substance; and response to xenobiotic stimulus. Predicted to localize to cytoplasm; nucleus; and transcription regulator complex. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator).
Genome Resources: Alliance (1),  Gene:493634 (1),  Ensembl(GRCz11):ENSDARG00000021855 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012987Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16681 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36026 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44836 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa45561 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-arnt
    1
    MO1-arnt N/A 8
    PHENOTYPE
    Data: Fig. 2 from Vettori et al., 2017
    Observed in:
    DISEASE ASSOCIATED WITH arnt HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arnt VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arnt-201 (1)    Ensembl 1828
    arnt-202 (1)    Ensembl 2540
    arnt-203 (1)    Ensembl 2060
    arnt-204 (1)    Ensembl 1935
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arnt No data available
    MARKER RELATIONSHIPS
    arnt Contained in: [BAC] CH211-256M12 (1)
    arnt Encodes: [cDNA] MGC:136664 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001011712 (1) 2108 nt
    Genomic GenBank:BX927222 (1) 154714 nt
    Select Tool
    Polypeptide UniProtKB:E7FDK6 (1) 731 aa
    Sequence Information (all 32)
    ORTHOLOGY for arnt ( Chr: 16 )
    CITATIONS (38)