ZFIN ID: ZDB-GENE-051113-64
|
Gene Name: |
transcription factor 3b
|
Gene Symbol: |
tcf3b
Nomenclature History
|
|
Previous Names:
|
tcf3a (1),
zgc:113045
|
Attributions for Alias: {{control.newAlias}}
Delete Alias:
(Including Attributions)
|
Gene Type: |
protein_coding_gene
|
Location: |
Chr:
22
Mapping Details/Browsers
|
|
Description: |
Predicted to have several functions, including DNA-binding transcription factor activity; bHLH transcription factor binding activity; and protein dimerization activity. Predicted to be involved in positive regulation of neuron differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in agammaglobulinemia and colorectal cancer. Orthologous to human TCF3 (transcription factor 3).
|
Genome Resources:
|
Alliance
(1),
Gene:664768
(1),
Ensembl(GRCz11):ENSDARG00000099999
(1)
|
MUTATIONS AND SEQUENCE TARGETING REAGENTS
PHENOTYPE
No data available
DISEASE ASSOCIATED WITH tcf3b HUMAN ORTHOLOG
Disease Ontology Term |
Multi-Species Data |
OMIM Term |
OMIM Phenotype ID |
|
|
Agammaglobulinemia 8, autosomal dominant |
616941 |
DISEASE ASSOCIATED WITH tcf3b VIA EXPERIMENTAL MODELS
No data available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM tcf3b
ORTHOLOGY for tcf3b (
Chr:
22
)