Gene

grk7a

ID
ZDB-GENE-050824-1
Name
G protein-coupled receptor kinase 7a
Symbol
grk7a Nomenclature History
Previous Names
  • grk7-1 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits photoreceptor activity and rhodopsin kinase activity. Involved in cone photoresponse recovery; phototransduction, visible light; and visual perception. Predicted to localize to membrane. Is expressed in brain; epiphysis; eye; retinal cone cell; and retinal photoreceptor layer. Orthologous to human GRK7 (G protein-coupled receptor kinase 7).
Genome Resources
Note
None
Expression
All Expression Data
19 figures from 10 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grk7a Human Ortholog
No data available
Associated With grk7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR016137 RGS domain
Family IPR000239 GPCR kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036305 RGS domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal GPCR kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily RGS domain RGS domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q49HM9 549
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-grk7a polyclonal Rabbit
  • IHC
  • WB
5
Ab4-grk7 polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations