ZFIN ID: ZDB-GENE-050823-4
Gene Name: cadherin EGF LAG seven-pass G-type receptor 1b
Gene Symbol: celsr1b    Nomenclature History

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Previous Names: celsr5, fmi1b (1), flamingo 1b (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity and calcium ion binding activity. Involved in cell migration involved in gastrulation; heart development; and neural tube development. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in brain; head; heart; and pleuroperitoneal region. Orthologous to human CELSR1 (cadherin EGF LAG seven-pass G-type receptor 1).
Genome Resources: Alliance (1),  Gene:556520 (1),  Ensembl(GRCz11):ENSDARG00000058259 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023202Tg Transgenic Insertion Unknown Unknown DNA
la023203Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028686Tg Transgenic Insertion Unknown Unknown DNA
    la028687Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa426 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10133 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11458 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa12090 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12454 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13613 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24665 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44288 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-celsr1b N/A 1
    MO2-celsr1b N/A 1
    MO3-celsr1b N/A 2
    MO4-celsr1b N/A 2
    MO5-celsr1b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH celsr1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH celsr1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration involved in gastrulation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA celsr1b-201 (1)    Ensembl 9761
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM celsr1b No data available
    MARKER RELATIONSHIPS
    celsr1b Contained in: [BAC] CH73-230F23 (1), CH211-270M7 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001920737 (1) 9577 nt
    Genomic GenBank:CU041386 (1) 126753 nt
    Select Tool
    Polypeptide UniProtKB:F1QBS8 (1) 3006 aa
    Sequence Information (all 11)
    ORTHOLOGY for celsr1b ( Chr: 25 )
    CITATIONS (29)