Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050706-192
Gene Name: anti-Mullerian hormone
Gene Symbol: amh
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 8 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  granulosa cell layer, ovary, reproductive system, Sertoli cell cytoplasm (all 7) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa24159
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Persistent Mullerian duct syndrome, type I 261550
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of androgen secretion (more)
Cellular Component extracellular region (more)
Molecular Function growth factor activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001839 (1)
  • InterPro:IPR006799 (1)
  • InterPro:IPR021203 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF04709 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA amh-001 (1) 3243
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-amh (1), Ab2-amh (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM amh
    Tg(amh-LOXP-CMV:NPT-HcRed-LOXP-baxb,baxa)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    amh Contained in: [BAC] DKEY-211F22 (1)
    amh Encodes: [EST] fo84g06
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007779 (1) 1650 bp
    Genomic GenBank:BX005098 (1) 100658 bp
    Select Tool
    Polypeptide UniProtKB:A8E7B8 (1) 549 aa
    Sequence Clusters UniGene:120159 (1)
    Sequence Information (all 17)
    OTHER amh GENE PAGES
  • Gene:493624 (1)
  • VEGA:OTTDARG00000014161 (1)
  • Ensembl(Zv9):ENSDARG00000014357 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish amh 22  
    Human AMH 19 (19p13.3)
  • OMIM:600957
  • Gene:268
  • Mouse Amh 10 ( 39.72 cM)
  • MGI:88006
  • Gene:11705
  • Orthology Details
    CITATIONS (37)