ZFIN ID: ZDB-GENE-050626-142
Gene Name: alkaline phosphatase, intestinal, tandem duplicate 2
Gene Symbol: alpi.2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fb68b10, si:ch211-262h13.2 (1), wu:fb68b10 (1), zgc:110409 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have phosphatase activity. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Is expressed in intestinal bulb; intestine; and yolk syncytial layer. Orthologous to several human genes including ALPI (alkaline phosphatase, intestinal).
Genome Resources: Alliance (1),  Gene:574009 (1),  Ensembl(GRCz11):ENSDARG00000053774 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (8 images) from Thisse et al., 2004 [MGC:110409]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32417 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH alpi.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH alpi.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component plasma membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001952 Alkaline phosphatase
    Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA alpi.2-201 (1)    Ensembl 2566
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM alpi.2 No data available
    MARKER RELATIONSHIPS
    alpi.2 Contained in: [BAC] CH211-262H13 (1)
    alpi.2 Encodes: [EST] fb68b10 (1)
    [cDNA] MGC:110409 (1), MGC:191443 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001025188 (1) 2407 bp
    Genomic GenBank:BX927181 (1) 68264 bp
    Select Tool
    Polypeptide UniProtKB:F1QNK5 (1) 530 aa
    Sequence Information (all 21)
    ORTHOLOGY for alpi.2 ( Chr: 22 )
    CITATIONS (19)