Community Action Needed: Please respond to the NIH RFI
Gene

alpi.2

ID
ZDB-GENE-050626-142
Name
alkaline phosphatase, intestinal, tandem duplicate 2
Symbol
alpi.2 Nomenclature History
Previous Names
  • fb68b10
  • si:ch211-262h13.2 (1)
  • wu:fb68b10 (1)
  • zgc:110409 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable alkaline phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Predicted to be anchored component of membrane. Predicted to be active in plasma membrane. Is expressed in intestinal bulb; intestine; and yolk syncytial layer. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to several human genes including ALPI (alkaline phosphatase, intestinal).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alpi.2 Human Ortholog
No data available
Associated With alpi.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001952 Alkaline phosphatase
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline phosphatase Alkaline-phosphatase-like, core domain superfamily
UniProtKB:E7F8M7 521
UniProtKB:A0A2R8QA11 529
UniProtKB:F1QNK5 530
UniProtKB:Q4QRJ9 521
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations