Gene

gja8a

ID
ZDB-GENE-050616-14
Name
gap junction protein alpha 8 paralog a
Symbol
gja8a Nomenclature History
Previous Names
  • cx50.5
  • cx79.8 (1)
  • si:dkey-18p12.7
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to localize to connexin complex. Is expressed in eye. Human ortholog(s) of this gene implicated in cataract and cataract 1 multiple types. Orthologous to human GJA8 (gap junction protein alpha 8).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gja8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cataract 1 multiple types Alliance Cataract 1, multiple types 116200
Associated With gja8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017990 Connexin, conserved site
Domain IPR013092 Connexin, N-terminal
Domain IPR019570 Gap junction protein, cysteine-rich domain
Family IPR000500 Connexin
Family IPR002266 Gap junction alpha-8 protein (Cx50)
Homologous_superfamily IPR038359 Connexin, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Connexin Connexin, conserved site Connexin, N-terminal Connexin, N-terminal domain superfamily Gap junction alpha-8 protein (Cx50) Gap junction protein, cysteine-rich domain
UniProtKB:C7E643 380
UniProtKB:B0S6Z4 709
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-gja8a polyclonal Rabbit
  • IHC
1
Ab2-gja8a polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations