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General Information
ZIRC
ZFIN ID: ZDB-GENE-050601-2
Gene Name: tumor necrosis factor b (TNF superfamily, member 2)
Gene Symbol: tnfb
Sequence Ontology ID : SO:0000704

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Previous Names: TNF2 (1), tnf, lta (1), TNF-alpha 2 (1), Tnf-alpha (1)

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity and tumor necrosis factor receptor binding activity. Involved in liver development. Predicted to localize to the extracellular space and integral component of  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22693 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22694 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Qi et al., 2010
    Observed in:
    DISEASE ASSOCIATED WITH tnfb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    migraine {Migraine without aura, susceptibility to} 157300
    {Dementia, vascular, susceptibility to}
    {Septic shock, susceptibility to}
    {Asthma, susceptibility to} 600807
    {Malaria, cerebral, susceptibility to} 611162
    DISEASE ASSOCIATED WITH tnfb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component extracellular space (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA tnfb-002 (1) 759
    mRNA tnfb-201 (1) 1243
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tnfb No data available
    MARKER RELATIONSHIPS
    tnfbContained in: [BAC] CH73-108E8 (1) (order this), DKEY-148A13 (1) (order this)
    tnfbEncodes: [cDNA] MGC:136314 (1) (order this), MGC:192001 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001024447 (1) 1220bp
    Genomic GenBank:BX629345 (1) 133660bp
    Select Tool
    Polypeptide UniProtKB:Q1JQ40 (1) 242aa
    Sequence Clusters UniGene:94015 (1)
    Sequence Information (all 19)
    ORTHOLOGY for tnfb (Chr: 15)
    CITATIONS (75)