ZFIN ID: ZDB-GENE-050522-264
Gene Name: granulin 2
Gene Symbol: grn2    Nomenclature History

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Previous Names: wu:fb14a12, zgc:111860

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to be involved in regulation of nervous system development. Predicted to localize to extracellular region. Is expressed in brain; digestive system; gill; pharyngeal arch; and pleuroperitoneal region.
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000088641 (1)
GENE EXPRESSION
All Expression Data: 14 figures from 4 publications
Directly Submitted Expression Data: 7 figures (3 images) from Thisse et al., 2004 [MGC:111860]
  1 figure (1 image) from Thisse et al., 2005 [eu841]
  1 figure (1 image) from Thisse et al., 2005 [eu849]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13899 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43332 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grn2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grn2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of nervous system development (more)
    Cellular Component extracellular region (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grn2-201 (1)    Ensembl 668
    grn2-202 (1)    Ensembl 783
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grn2 No data available
    MARKER RELATIONSHIPS
    grn2 Contained in: [BAC] CH211-173P18 (1)
    grn2 Encodes: [EST] eu841 (1), eu849 (1), fb14a12 (1)
    [cDNA] MGC:111860 (1), MGC:191916 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA GenBank:BC095576 (1) 749 nt
    Genomic GenBank:BX510986 (1) 157245 nt
    Select Tool
    Polypeptide UniProtKB:I3IT60 (1) 152 aa
    Sequence Information (all 12)
    ORTHOLOGY for grn2 ( Chr: 19 )
    CITATIONS (31)