Gene

actl6b

ID
ZDB-GENE-050522-191
Name
actin-like 6B
Symbol
actl6b Nomenclature History
Previous Names
  • zgc:110167
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Is predicted to enable chromatin binding activity. Involved in chromatin organization; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to be part of NuA4 histone acetyltransferase complex and SWI/SNF complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 76. Orthologous to human ACTL6B (actin like 6B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With actl6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 76 Alliance Developmental and epileptic encephalopathy 76 618468
Intellectual developmental disorder with severe speech and ambulation defects 618470
Associated With actl6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR004001 Actin, conserved site
Family IPR004000 Actin family
Homologous_superfamily IPR043129 ATPase, nucleotide binding domain
Domain Details Per Protein
Protein Length Actin, conserved site Actin family ATPase, nucleotide binding domain
UniProtKB:Q503T4 376
UniProtKB:F8W3Z2 426
UniProtKB:E7F7V5 376
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations